4-Nitrobenzaldehyde → Ethyl 2-methyl-3-(4-nitrophenyl)prop-2-enoate

反応式

C1(P(C2C=CC=CC=2)(C2C=CC=CC=2)=[C:8]([C:10]([O:12][CH2:13][CH3:14])=[O:11])[CH3:9])C=CC=CC=1.[N+:27]([C:30]1[CH:37]=[CH:36][C:33]([CH:34]=O)=[CH:32][CH:31]=1)([O-:29])=[O:28]>>[CH3:9][C:8](=[CH:34][C:33]1[CH:36]=[CH:37][C:30]([N+:27]([O-:29])=[O:28])=[CH:31][CH:32]=1)[C:10]([O:12][CH2:13][CH3:14])=[O:11]

参加物

反応物 2

HCID 5414-Nitrobenzaldehyde

HCID 79792Ethyl 2-(triphenylphosphoranylidene)propionate

生成物 1

HCID 54080096Ethyl 2-methyl-3-(4-nitrophenyl)prop-2-enoate収率 56%

実験手順

The title compound was prepared from triphenyl(1-[ethoxycarbonyl]ethylidene)phosphorane and 4-nitrobenzaldehyde, substantially according to Preparation 5. The product was obtained in 56% yield, as an orange-yellow solid, m.p. 70.5°-73° C.

後処理

customsubstantially according to Preparation 5
customThe product was obtained in 56% yield, as an orange-yellow solid, m.p. 70.5°-73° C.

出典と根拠

ORDレコード: ord-d9422bcd252746eab56c8f49757741ff
出典データセット: uspto-grants-1982_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04343813

反応ノート

読み込み中…

参加物