化工社化工社 化学情報印刷レポート · 研究参考用
Benzyl Bromide → 5-benzyloxy-3-phenyl-1H-2-indole-carboxylic acid ethylester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzyl Bromide | HCID 7498 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Ethyl 5-hydroxy-3-phenyl-1H-indole-2-carboxylate | HCID 11550917 | — |
| 溶媒 | Methyl Ethyl Ketone | HCID 6569 | — |
| 生成物 | 5-benzyloxy-3-phenyl-1H-2-indole-carboxylic acid ethylester | HCID 4777862 | — |
反応手順
Twenty-six grams (92.4 m mole) of 5-hydroxy-3-phenyl-1H-2-indole carboxylic acid ethylester were refluxed for four days with 27.6 g of potassium carbonate and 11 ml (92.4 mole) of benzylbromide in 700 ml of methyl-ethylketone. After filtration and evaporation, the residue was chromatographed on silicagel (solvent: toluene).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04343811 |
| 出典データセット | uspto-grants-1982_08 |
| ORD ID | ord-0cfe56dcc81144c48b41a140a5ebcfd0 |
| 出典メモ | uspto-grants-1982_08 |