Sodium Chloride → HCID 20529096、化合物

HRID 66827ノート

反応式

HRID 66827 の反応式
C(OC([CH:6]1[CH2:33][CH2:32][CH2:31][N:9]2[C:10]3[C:15]([C:16]([C:17]4[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=4)=[C:8]2[C:7]1=[O:34])=[CH:14][C:13]([O:23][CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)=[CH:12][CH:11]=3)=O)C.[Cl-].[Na+]>CS(C)=O.O.C(OCC)(=O)C>[CH2:24]([O:23][C:13]1[CH:14]=[C:15]2[C:10](=[CH:11][CH:12]=1)[N:9]1[CH2:31][CH2:32][CH2:33][CH2:6][C:7](=[O:34])[C:8]1=[C:16]2[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1

参加物

6

反応物 2

HCID 5234Sodium ChlorideHCID 538189352-benzyloxy-7,8,9,10-tetrahydro-10-oxo-11-phenyl-6H-9-azepino[1,2-a]indole carboxylic acid ethylester

生成物 1

HCID 20529096HCID 20529096、化合物

試薬・触媒・溶媒 3

HCID 679Dimethyl Sulfoxide溶媒HCID 962Water溶媒HCID 8857Ethyl Acetate溶媒

実験手順

An amount of 2.8 g (6.17 m mole) of 2-benzyloxy-7,8,9,10-tetrahydro-10-oxo-11-phenyl-6H-9-azepino[1,2-a]indole carboxylic acid ethylester and 0.36 g (6.1 m mole) of sodium chloride were refluxed for four hours in 3.5 ml of dimethylsulfoxide and 0.35 ml of water. After cooling, the mixture was taken up in ethyl acetate, dried over sodium sulfate, suction filtered, and evaporated. The residue was triturated with petroleum ether and suction filtered.

後処理

  1. temperatureAfter cooling
  2. dry with materialdried over sodium sulfate, suction
  3. filtrationfiltered
  4. customevaporated
  5. customThe residue was triturated with petroleum ether and suction
  6. filtrationfiltered

出典と根拠

ORDレコード
ord-929c433145c4403784e80209aaed0953
出典データセット
uspto-grants-1982_08
特許番号
US04343811

反応ノート

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