Hydrochloric Acid → 2-Methyl-2-[3-methyl-1-propyl-2-(4-pyridyl)-1H-indole-5-yloxy]propanoic acid hydrochloride

HRID 66888ノート

反応式

HRID 66888 の反応式
C([O:3][C:4](=[O:28])[C:5]([CH3:27])([O:7][C:8]1[CH:9]=[C:10]2[C:14](=[CH:15][CH:16]=1)[N:13]([CH2:17][CH2:18][CH3:19])[C:12]([C:20]1[CH:25]=[CH:24][N:23]=[CH:22][CH:21]=1)=[C:11]2[CH3:26])[CH3:6])C.[ClH:29]>>[ClH:29].[CH3:6][C:5]([O:7][C:8]1[CH:9]=[C:10]2[C:14](=[CH:15][CH:16]=1)[N:13]([CH2:17][CH2:18][CH3:19])[C:12]([C:20]1[CH:25]=[CH:24][N:23]=[CH:22][CH:21]=1)=[C:11]2[CH3:26])([CH3:27])[C:4]([OH:28])=[O:3]

参加物

3

反応物 2

HCID 313Hydrochloric AcidHCID 538957452-methyl-2-[3-methyl-1-propyl-2-(4-pyridyl)-1H-indole-5-yloxy]propanoic acid ethylester

生成物 1

HCID 705486392-Methyl-2-[3-methyl-1-propyl-2-(4-pyridyl)-1H-indole-5-yloxy]propanoic acid hydrochloride

実験手順

The above compound was prepared from 2-methyl-2-[3-methyl-1-propyl-2-(4-pyridyl)-1H-indole-5-yloxy]propanoic acid ethylester by hydrolysis with diluted hydrochloric acid at the boiling temperature. After the hydrochloric acid was distilled off in vacuo, the reaction product was recrystallized from acetone.

後処理

  1. distillationAfter the hydrochloric acid was distilled off in vacuo
  2. customthe reaction product was recrystallized from acetone

出典と根拠

ORDレコード
ord-406739993b464f6e85a11eda7de205f7
出典データセット
uspto-grants-1982_08
特許番号
US04343811

反応ノート

読み込み中…