関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Benzoyl chloride | HCID 7412 | — |
| 反応物 | 3-(Trichloromethyl)-1,2,4-thiadiazol-5-amine | HCID 602848 | — |
| 溶媒 | O-Xylene | HCID 7237 | — |
| 生成物 | 5-Benzamido-3-Trichloromethyl-1,2,4-Thiadiazole | HCID 12851601 | 85% |
反応手順
A solution of 11.0 g (0.05 mole) 5-amino-3-trichloromethyl-1,2,4-thiadiazole and 14.1 g (0.1 mole) benzoyl chloride in 200 ml xylene was heated at reflux for 20 hours. Upon cooling to -10° C., 13.7 g (85% yield) of pure product precipitated from the reaction mixture and was isolated by filtration; m.p. 190° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04343945 |
|---|
| 出典データセット | uspto-grants-1982_08 |
|---|
| ORD ID | ord-1f492a9cadcf4eea91bdcf7b79a7d5e6 |
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| 出典メモ | uspto-grants-1982_08 |
|---|
