化工社化工社 化学情報印刷レポート · 研究参考用
Iodine → 5,5-Dimethyl-1-iodo-trans-octen-3-ol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Iodine | HCID 807 | — |
| 反応物 | Trimethylamine oxide | HCID 1145 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Bis(1,2-dimethylpropyl)borane | HCID 192733 | — |
| 反応物 | 5,5-Dimethyl-3-tetrahydropyranyloxy-1-octyne | HCID 53889730 | — |
| 反応物 | Tetrahydrofuranacetic acid water | HCID 86732972 | — |
| 溶媒 | Diglyme | HCID 8150 | — |
| 生成物 | 5,5-Dimethyl-1-iodo-trans-octen-3-ol | HCID 20465606 | — |
反応手順
Treatment of 23.8 g. (0.100 mole) of 5,5-dimethyl-3-tetrahydropyranyloxy-1-octyne (Example 999) successively with 233 ml. of 0.43 M disiamylborane in diglyme, 22.5 g. of trimethylamine oxide, 150 ml. of 1 N sodium hydroxide, 25.4 g. of iodine, and 900 ml. of 3:1:1 tetrahydrofuranacetic acid-water as described in Example 996 gives the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04343949 |
| 出典データセット | uspto-grants-1982_08 |
| ORD ID | ord-f75259f3d49b43d6acb4b73ba456781c |
| 出典メモ | uspto-grants-1982_08 |