反応式
[OH:1][CH:2]1[CH2:6][CH:5]=[CH:4][CH:3]1/[CH:7]=[CH:8]\[CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14].CC(C)=O.[Cr](O)(O)(=O)=O>S(=O)(=O)(O)O>[C:13]([CH2:12][CH2:11][CH2:10][CH2:9]/[CH:8]=[CH:7]\[CH:3]1[CH:4]=[CH:5][CH2:6][C:2]1=[O:1])([OH:15])=[O:14]参加物
5
実験手順
A solution of 3.2 g. (0.5 mole) of 1-hydroxy-2-(6-carboxy-2-cis-hexenyl)cyclopent-3-ene (Example 1132) in 60 ml. of reagent acetone is treated dropwise with a total of 6 ml. of 8 N chromic acid in sulfuric acid at 0° C. The oxidation is rather slow. The resulting mixture is dissolved in 200 ml. of water and the solution is extracted with six 50 ml portions of ether. The combined ethereal extracts are dried over sodium sulfate and the solvent is evaporated at reduced pressure to yield the product as a yellow oil.
後処理
- customat 0° C
- dissolutionThe resulting mixture is dissolved in 200 ml
- extractionof water and the solution is extracted with six 50 ml portions of ether
- dry with materialThe combined ethereal extracts are dried over sodium sulfate
- customthe solvent is evaporated at reduced pressure
出典と根拠
- ORDレコード
- ord-13f5871605f04517a30b3a728b0bbfa8
- 出典データセット
- uspto-grants-1982_08
- 特許番号
- US04343949
関連ノート
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