化工社化工社 化学情報印刷レポート · 研究参考用
2-Ethylpiperidine → 2,6-Bis-(2-ethylpiperidino-acetylamino)-benzo[1,2-d:5,4-d']bisthiazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Ethylpiperidine | HCID 94205 | — |
| 反応物 | 2,6-Bis-(chloroacetyl-amino)benzo[1,2-d:5,4-d']bisthiazole | HCID 15754641 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | 2-Amino-6-(2-ethylpiperidino-acetylamino)-benzo[1,2-d:5,4-d']bisthiazole | HCID 20528193 | 37% |
| 生成物 | 2,6-Bis-(2-ethylpiperidino-acetylamino)-benzo[1,2-d:5,4-d']bisthiazole | HCID 70547781 | 47% |
反応手順
A mixture of 8.0 gm of 2,6-bis-(chloroacetyl-amino)benzo[1,2-d:5,4-d']bisthiazole, 10.0 gm of 2-ethyl-piperidine and 100 ml of dioxane was refluxed for 2 hours. The reaction mixture was worked up as described in Example 16; the compounds (a) (47% of theory, from ethanol), M.P. 201°-203° C., and (b) (37% of theory, from ethanol), M.P. 223°-225° C. were isolated.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04344946 |
| 出典データセット | uspto-grants-1982_08 |
| ORD ID | ord-94e274c4bcfd482bbb4f48b3715bdd29 |
| 出典メモ | uspto-grants-1982_08 |