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Carbon Dioxide → 6-Hydroxy-2-naphthoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Carbon Dioxide | HCID 280 | — |
| 反応物 | 2-Naphthol | HCID 8663 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 生成物 | 3-Hydroxy-2-naphthoic acid | HCID 7104 | — |
| 生成物 | 6-Hydroxy-2-naphthoic acid | HCID 85557 | 48.1% |
反応手順
The procedure of Example 1 is followed in every detail except that a mixture of 2-hydroxynaphthalene (83 grams; 0.576 mole), 45% potassium hydroxide (69.7 grams; 0.559 mole), and potassium carbonate (20 grams; 0.145 mole) is employed initially, the dehydrated reaction mixture is heated under 60 psi of carbon dioxide for 10 hours, and the aqueous phase is washed twice with 100-ml portions of isopropylnaphthalene at 85°-95° C. There is obtained 25.5 grams of 6-hydroxy-2-naphthoic acid (48.1% of theoretical), and 4.6 grams of 3-hydroxy-2-naphthoic acid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04345094 |
| 出典データセット | uspto-grants-1982_08 |
| ORD ID | ord-4dfb55a228b64a9aaa64bd694a289a5f |
| 出典メモ | uspto-grants-1982_08 |