Toluene → ethyl 2-(5-azido-7-bromo-3-chloro-5H-chromeno[2,3-c]pyridin-5-yl)acetate

反応式

[Br:1][c:2]1[cH:3][c:4]2[c:14]([cH:15][cH:16]1)[O:13][c:7]1[c:6]([cH:11][c:10]([Cl:12])[n:9][cH:8]1)[C:5]2([OH:17])[CH2:18][C:19](=[O:20])[O:21][CH2:22][CH3:23].[CH3:31][c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1.[N:24](=[N+:25]=[N-:26])[Si:27]([CH3:28])([CH3:29])[CH3:30]>>[Br:1][c:2]1[cH:3][c:4]2[c:14]([cH:15][cH:16]1)[O:13][c:7]1[c:6]([cH:11][c:10]([Cl:12])[n:9][cH:8]1)[C:5]2([CH2:18][C:19](=[O:20])[O:21][CH2:22][CH3:23])[N:24]=[N+:25]=[N-:26]

参加物

反応物 3

HCID 1140Toluene

HCID 78378Azidotrimethylsilane

HCID 86658372ethyl 2-(7-bromo-3-chloro-5-hydroxy-5H-chromeno[2,3-c]pyridin-5-yl)acetate

生成物 1

HCID 86658373ethyl 2-(5-azido-7-bromo-3-chloro-5H-chromeno[2,3-c]pyridin-5-yl)acetate

出典と根拠

ORDレコード: ord-d82834b2f89549de969a3d03e0793f2d
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…