化工社化工社 化学情報印刷レポート · 研究参考用
Acetic Anhydride → (RS)-Salsolinol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Anhydride | HCID 7918 | — |
| 反応物 | Homoveratrylamine | HCID 8421 | — |
| 反応物 | Propionyl chloride | HCID 62324 | — |
| 反応物 | 2-(4-Methoxy-3-methylphenyl)ethan-1-amine | HCID 6484660 | — |
| 反応物 | N-Ethyl-4-methoxybenzenamine | HCID 11804947 | — |
| 生成物 | (RS)-Salsolinol | HCID 54456 | — |
| 生成物 | 1,6-Dimethyl-1,2,3,4-tetrahydro-isoquinolin-7-ol | HCID 22018488 | — |
| 生成物 | 1-Ethyl-1,2,3,4-tetrahydro-isoquinolin-7-ol | HCID 22018521 | — |
反応手順
Similarly, 1-ethyl-1,2,3,4-tetrahydro-isoquinolin-7-ol was prepared by the above procedures by replacing the acetic anhydride in Procedure EEE with propionyl chloride. 1-Methyl-1,2,3,4-tetrahydro-isoquinoline-6,7-diol and 1,6-dimethyl-1,2,3,4-tetrahydro-isoquinolin-7-ol were prepared by replacing the (4-methoxy-phenyl)-ethylamine in procedure EEE with 3,4-dimethoxyphenylethylamine and 3-methyl-4-methoxyphenylethylamine, respectively.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07084154B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-e7cbb3815910472891528b46b72c15cf |
| 出典メモ | uspto-grants-2006_08 |