Octanoic Acid → 4-Octamidoethyl-2,3,6,7-tetrahydro-1,4-diazocin-5-one

HRID 67681

反応式

HRID 67681 の反応式
[NH2:1][CH2:2][CH2:3][NH:4][CH2:5][CH2:6][NH2:7].[CH:8]([CH2:10][CH2:11][C:12]([O:14]CCC)=O)=O.[CH3:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][C:25](O)=[O:26]>>[C:25]([NH:1][CH2:2][CH2:3][N:4]1[C:12](=[O:14])[CH2:11][CH2:10][CH:8]=[N:7][CH2:6][CH2:5]1)(=[O:26])[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH3:18]

参加物

4

反応物 3

HCID 379Octanoic AcidHCID 8111DiethylenetriamineHCID 20478715Propyl 3-formylpropionate

生成物 1

HCID 1317128034-Octamidoethyl-2,3,6,7-tetrahydro-1,4-diazocin-5-one

実験手順

Into an apparatus similar to that in Example 1, were charged 103.1 g (1 mole) of diethylenetriamine and 144.2 g (1 mole) of propyl 3-formylpropionate. At 140° to 145° C., 18 g of water and 60 g of propyl alcohol were distilled off. Then, after adding 144.2 g (1 mole) of octylic acid, the reaction was allowed to proceed at 150° to 155° C. to distil off 18 g of water, obtaining 4-octamidoethyl-2,3,6,7-tetrahydro-1,4-diazocin-5-one.

後処理

  1. distillationAt 140° to 145° C., 18 g of water and 60 g of propyl alcohol were distilled off
  2. customto proceed at 150° to 155° C.
  3. customto distil off 18 g of water

出典と根拠

ORDレコード
ord-d4878d40f2dd4268b0fd220eb1447727
出典データセット
uspto-grants-1982_08
特許番号
US04346087

関連ノート

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