Benzoyl isothiocyanate → t-Butyl 3-amino-2-(N-benzoylthiocarbamoyl)crotonate
反応式
[NH2:1]/[C:2](/[CH3:11])=[CH:3]\[C:4]([O:6][C:7]([CH3:10])([CH3:9])[CH3:8])=[O:5].[C:12]([N:20]=[C:21]=[S:22])(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C(OCC)C>[NH2:1]/[C:2](/[CH3:11])=[C:3](/[C:21](=[S:22])[NH:20][C:12](=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)\[C:4]([O:6][C:7]([CH3:10])([CH3:9])[CH3:8])=[O:5]参加物
4
実験手順
A mixture of t-butyl 3-aminocrotonate (65.3 g, 0.4 mol), benzoyl isothiocyanate (62.9 g, 0.4 mol), and diethyl ether (300 ml) was stirred at ambient temperature for 3 hours. The solid product was collected on a filter, washed with ether and dried to give 56 g (43.7 percent yield) of material melting at 107° to 110° C.
後処理
- customThe solid product was collected on a filter
- washwashed with ether
- customdried
出典と根拠
- ORDレコード
- ord-cc77814a74d2420aaccab410ffc05e63
- 出典データセット
- uspto-grants-1982_08
- 特許番号
- US04346161
反応ノート
読み込み中…