Phosphorus oxide (P4O10) → 4-(4-Chloro-3-chlorosulfonylphenyl)-3-methyl-2-phenylimino-4-thiazoline hydrobromide

HRID 67778ノート

反応式

HRID 67778 の反応式
[BrH:1].[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2(O)[CH2:13][S:12][C:11](=[N:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[N:10]2[CH3:21])=[CH:5][C:4]=1[S:23]([Cl:26])(=[O:25])=[O:24].O=P12OP3(OP(OP(O3)(O1)=O)(=O)O2)=O>O>[BrH:1].[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:10]([CH3:21])[C:11](=[N:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[S:12][CH:13]=2)=[CH:5][C:4]=1[S:23]([Cl:26])(=[O:24])=[O:25]

参加物

4

反応物 2

HCID 14812Phosphorus oxide (P4O10)HCID 205273174-(4-Chloro-3-chlorosulfonylphenyl)-3-methyl-2-phenyliminothiazolidin-4-ol hydrobromide

生成物 1

HCID 205273464-(4-Chloro-3-chlorosulfonylphenyl)-3-methyl-2-phenylimino-4-thiazoline hydrobromide

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

2.5 g (50 mmoles) of 4-(4-chloro-3-chlorosulfonylphenyl)-3-methyl-2-phenyliminothiazolidin-4-ol hydrobromide are heated rapidly in a jacket, which has been preheated to 220° C., in vacuo (0.1 mm Hg) over phosphorus pentoxide. The substance melts with foaming, as a result of the elimination of water, and solidifies immediately after the end of the reaction, with recrystallization. Slightly green colored crystals; melting point 264° C.

後処理

  1. customafter the end of the reaction
  2. customwith recrystallization

出典と根拠

ORDレコード
ord-d5bdb40cd2b5457ca0efdf1021e3579c
出典データセット
uspto-grants-1982_08
特許番号
US04346088

反応ノート

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