4-(Chloromethyl)pyridine → tert-butyl (3RS,4RS)-3-(naphthalen-2-ylmethoxy)-4-{4-[2-(pyridin-4-ylmethoxy)-ethoxy)-phenyl}-piperidine-1-carboxylate

反応式

[Cl:36][CH2:37][c:38]1[cH:39][cH:40][n:41][cH:42][cH:43]1.[OH:1][CH2:2][CH2:3][O:4][c:5]1[cH:6][cH:7][c:8]([CH:11]2[CH:12]([O:24][CH2:25][c:26]3[cH:27][c:28]4[cH:29][cH:30][cH:31][cH:32][c:33]4[cH:34][cH:35]3)[CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]2)[cH:9][cH:10]1>>[O:1]([CH2:2][CH2:3][O:4][c:5]1[cH:6][cH:7][c:8]([CH:11]2[CH:12]([O:24][CH2:25][c:26]3[cH:27][c:28]4[cH:29][cH:30][cH:31][cH:32][c:33]4[cH:34][cH:35]3)[CH2:13][N:14]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:15][CH2:16]2)[cH:9][cH:10]1)[CH2:37][c:38]1[cH:39][cH:40][n:41][cH:42][cH:43]1

参加物

反応物 2

HCID 745714-(Chloromethyl)pyridine

HCID 54366502tert-butyl (3RS,4RS)-4-(4-(2-hydroxy-ethoxy)-phenyl]-3-(naphthalen-2-ylmethoxy)-piperidine-1-carboxylate

生成物 1

HCID 54161995tert-butyl (3RS,4RS)-3-(naphthalen-2-ylmethoxy)-4-{4-[2-(pyridin-4-ylmethoxy)-ethoxy)-phenyl}-piperidine-1-carboxylate

出典と根拠

ORDレコード: ord-c2adcbaf3a844199b06d75bab6f04b6f
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…