Dichloromethane → 1-[4-[6-Bromo-2-(2-hydroxyphenyl)quinazolin-4-yl]piperazin-1-yl]-2-hydroxy-4-methylpentan-1-one

反応式

[Br:1][c:2]1[cH:3][c:4]2[c:5]([Cl:19])[n:6][c:7](-[c:12]3[c:13]([OH:18])[cH:14][cH:15][cH:16][cH:17]3)[n:8][c:9]2[cH:10][cH:11]1.[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[Cl:41][CH2:42][Cl:43].[OH:20][CH:21]([C:22](=[O:23])[N:24]1[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]1)[CH2:30][CH:31]([CH3:32])[CH3:33]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([N:27]3[CH2:26][CH2:25][N:24]([C:22]([CH:21]([OH:20])[CH2:30][CH:31]([CH3:32])[CH3:33])=[O:23])[CH2:29][CH2:28]3)[n:6][c:7](-[c:12]3[c:13]([OH:18])[cH:14][cH:15][cH:16][cH:17]3)[n:8][c:9]2[cH:10][cH:11]1