1-(4-amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine → N-(4-(4-(Dimethylamino)piperidin-1-yl)-2-methoxyphenyl)-4-(1H-indol-3-yl)-5-methylpyrimidin-2-amine

反応式

[Cl:1][c:2]1[n:3][cH:4][c:5]([CH3:17])[c:6](-[c:8]2[cH:9][nH:10][c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]23)[n:7]1.[NH2:18][c:19]1[c:20]([O:34][CH3:35])[cH:21][c:22]([N:25]2[CH2:26][CH2:27][CH:28]([N:31]([CH3:32])[CH3:33])[CH2:29][CH2:30]2)[cH:23][cH:24]1>>[c:2]1([NH:18][c:19]2[c:20]([O:34][CH3:35])[cH:21][c:22]([N:25]3[CH2:26][CH2:27][CH:28]([N:31]([CH3:32])[CH3:33])[CH2:29][CH2:30]3)[cH:23][cH:24]2)[n:3][cH:4][c:5]([CH3:17])[c:6](-[c:8]2[cH:9][nH:10][c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]23)[n:7]1

参加物

反応物 2

HCID 574161531-(4-amino-3-methoxyphenyl)-N,N-dimethylpiperidin-4-amine

HCID 580714243-(2-Chloro-5-methylpyrimidin-4-yl)-1H-indole

生成物 1

HCID 58071453N-(4-(4-(Dimethylamino)piperidin-1-yl)-2-methoxyphenyl)-4-(1H-indol-3-yl)-5-methylpyrimidin-2-amine

出典と根拠

ORDレコード: ord-314c26ecef834d7bbfb10aec55bf0a76
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…