Ethylamine → 2-(Ethylamino)nicotinonitrile
反応式
Cl[C:2]1[N:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[CH2:10]([NH2:12])[CH3:11]>O>[CH2:10]([NH:12][C:2]1[N:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5])[CH3:11]参加物
4
実験手順
A stirred mixture of 4 g. of 2-chloronicotinonitrile in 200 ml. of a saturated ethanolic ethylamine solution was heated under reflux for 5 hours. The solution was cooled and was diluted with 400 ml. of water. The precipitate of 2-ethylaminonicotinonitrile which formed was collected, air dried and was used directly in the next step without further purification.
後処理
- additionA stirred mixture of 4 g
- temperatureunder reflux for 5 hours
- temperatureThe solution was cooled
- additionwas diluted with 400 ml
出典と根拠
- ORDレコード
- ord-cbd57385fc3e447bbd56d4c7a65f522b
- 出典データセット
- uspto-grants-1982_08
- 特許番号
- US04347362
反応ノート
読み込み中…