Acetic Acid → HCID 136408868、化合物

HRID 67992ノート

反応式

HRID 67992 の反応式
[CH3:1][N:2]1[CH2:6][CH2:5][N:4]=[C:3]1[CH2:7][C:8]#[N:9].C(O)(=O)C.[N:14]([O-])=[O:15].[Na+]>O>[CH3:1][N:2]1[CH2:6][CH2:5][N:4]=[C:3]1[C:7](=[N:14][OH:15])[C:8]#[N:9]

参加物

5

反応物 3

HCID 176Acetic AcidHCID 201559001-Methyl-2-cyanomethyl-2-imidazolineHCID 23668193Sodium Nitrite

生成物 1

HCID 136408868HCID 136408868、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

12.3 g (0.1 mol) of 1-methyl-2-cyanomethyl-2-imidazoline are initially introduced into 50 ml of glacial acetic acid. A solution of 7.8 g (0.1 mol) of NaNO2 in 20 ml of water is added dropwise at about 15°, with cooling. The mixture is stirred for 2 hours, cooled and filtered and the residue is washed with a little cold water. This yields 11 g (=73% of theory) of end product, which is recrystallised from methanol; melting point 216.5° C.

後処理

  1. temperaturewith cooling
  2. temperaturecooled
  3. filtrationfiltered
  4. washthe residue is washed with a little cold water
  5. customThis yields 11 g (=73% of theory) of end product, which is recrystallised from methanol

出典と根拠

ORDレコード
ord-736866a998c54140b83a1f79828fe7a0
出典データセット
uspto-grants-1982_08
特許番号
US04347372

反応ノート

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