Dimethylformamide → 4-[4-(3-Chloro-4-morpholin-4-ylmethyl-phenyl)-1H-pyrazol-3-yl]-1H-pyrrole-2-carboxylic acid [1-(3-chloro-4-fluoro-phenyl)-2-hydroxy-ethyl]-amide

反応式

[Br:34][CH2:35][CH2:36][O:37][CH2:38][CH2:39][Br:40].[Cl:1][c:2]1[cH:3][c:4]([CH:9]([CH2:10][OH:11])[NH:12][C:13](=[O:14])[c:15]2[nH:16][cH:17][c:18](-[c:20]3[n:21][nH:22][cH:23][c:24]3-[c:25]3[cH:26][c:27]([Cl:33])[c:28]([CH2:31][NH2:32])[cH:29][cH:30]3)[cH:19]2)[cH:5][cH:6][c:7]1[F:8].[O:41]=[CH:42][N:43]([CH3:44])[CH3:45]>>[Cl:1][c:2]1[cH:3][c:4]([CH:9]([CH2:10][OH:11])[NH:12][C:13](=[O:14])[c:15]2[nH:16][cH:17][c:18](-[c:20]3[n:21][nH:22][cH:23][c:24]3-[c:25]3[cH:26][c:27]([Cl:33])[c:28]([CH2:31][N:32]4[CH2:35][CH2:36][O:37][CH2:38][CH2:39]4)[cH:29][cH:30]3)[cH:19]2)[cH:5][cH:6][c:7]1[F:8]