化工社化工社 化学情報印刷レポート · 研究参考用
Chloroacetyl chloride → 2-Chloro-N-(4-chlorobenzenesulfonyl)acetamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Chloroacetyl chloride | HCID 6577 | — |
| 反応物 | 4-Chlorobenzenesulfonamide | HCID 66824 | — |
| 生成物 | 2-Chloro-N-(4-chlorobenzenesulfonyl)acetamide | HCID 676503 | — |
反応手順
The reactant N-chloroacetyl 4-chlorobenzene sulfonamide was prepared by mixing 30.0 g of 4-chlorobenzene sulfonamide and 60.0 ml of chloroacetylchloride. The mixture was refluxed for 6 hours, allowed to cool, and stand at room temperature overnight. The crystalline product was removed by filtration, washed repeatedly with hexane, and dried. The product consisted of 32.5 g of reactant (m.p. 122°-124° C.). Structure was confirmed by IR and NMR.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04347380 |
| 出典データセット | uspto-grants-1982_08 |
| ORD ID | ord-9157d1aad09d476e98fe686e61eee7f5 |
| 出典メモ | uspto-grants-1982_08 |