化工社化工社 化学情報印刷レポート · 研究参考用
1,4-Dichlorobenzene → 2-Bromo-1,4-dichlorobenzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,4-Dichlorobenzene | HCID 4685 | — |
| 反応物 | Bromobenzene | HCID 7961 | — |
| 反応物 | Aluminum(III) Chloride | HCID 6451240 | — |
| 反応物 | 1,2-dibromo-3,4-dichlorobenzene | HCID 14029663 | — |
| 触媒 | Iron | HCID 23925 | — |
| 生成物 | 2-Bromo-1,4-dichlorobenzene | HCID 15033 | — |
| 生成物 | 4-Bromo-1,2-dichlorobenzene | HCID 29013 | — |
| 生成物 | 1-Bromo-2,4-dichlorobenzene | HCID 70947 | — |
反応手順
The o-, m- or p-dichlorobenzenes or mixture thereof which is used as intermediates for syntheses of various organic compounds is brominated at 0° to 100° C. in the presence of aluminum chloride, ferric chloride or iron powder. The bromobenzene is chlorinated in the same condition. The dichlorobenzene is reacted with the dibromodichlorobenzene in the presence of an aluminum halide for 1 to 5 hours. In these methods, 1-bromo-2,4-dichlorobenzene, 1-bromo-2,5-dichlorobenzene, and 1-bromo-3,4-dichlorobenzene etc. can be obtained in high yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04347390 |
| 出典データセット | uspto-grants-1982_08 |
| ORD ID | ord-12b808519d014a45884e6fff12f972d8 |
| 出典メモ | uspto-grants-1982_08 |