Methanol → N-ethyl-3-methyl-6-nitroquinolin-2-amine

反応式

Cl[C:2]1[C:11]([CH3:12])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([N+:13]([O-:15])=[O:14])[CH:8]=2)[N:3]=1.[CH2:16]([NH2:18])[CH3:17].CO>>[CH2:16]([NH:18][C:2]1[C:11]([CH3:12])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([N+:13]([O-:15])=[O:14])[CH:8]=2)[N:3]=1)[CH3:17]

参加物

反応物 3

HCID 887Methanol

HCID 6341Ethylamine

HCID 220190042-chloro-3-methyl-6-nitroQuinoline

生成物 1

HCID 22018880N-ethyl-3-methyl-6-nitroquinolin-2-amine

実験手順

The product (1 g, 4.5 mmol) from Step A and a solution of 2N ethylamine in methanol (5 mL, 25 mmol) were used to prepare the product according to the procedure of Example 1, Step C.

後処理

customto prepare the product

出典と根拠

ORDレコード: ord-6fe6e3cc88c24bf59c2bd7d84afa2c25
出典データセット: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07084156B2

反応ノート

読み込み中…