Dichloromethane → 5-bromo-N-(cis-4-methylcyclohexyl)-4-(1-(methylsulfonyl)azetidin-3-yloxy)pyrimidin-2-amine

反応式

[CH3:21][CH2:22][N:23]([CH2:24][CH3:25])[CH2:26][CH3:27].[CH3:28][S:29]([Cl:30])(=[O:31])=[O:32].[Cl:33][CH2:34][Cl:35].[NH:1]1[CH2:2][CH:3]([O:5][c:6]2[n:7][c:8]([NH:13][CH:14]3[CH2:15][CH2:16][CH:17]([CH3:20])[CH2:18][CH2:19]3)[n:9][cH:10][c:11]2[Br:12])[CH2:4]1>>[N:1]1([S:29]([CH3:28])(=[O:31])=[O:32])[CH2:2][CH:3]([O:5][c:6]2[n:7][c:8]([NH:13][CH:14]3[CH2:15][CH2:16][CH:17]([CH3:20])[CH2:18][CH2:19]3)[n:9][cH:10][c:11]2[Br:12])[CH2:4]1