2-Cyano-3-cyclohexyl-3-oxo-propionic acid ethyl ester → 3-Cyclohexyl-3-oxopropanenitrile
反応式
C(OC(=O)[CH:5]([C:14]#[N:15])[C:6]([CH:8]1[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1)=[O:7])C>CS(C)=O.O>[CH:8]1([C:6](=[O:7])[CH2:5][C:14]#[N:15])[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1参加物
3
実験手順
A solution of 2-cyano-3-cyclohexyl-3-oxo-propionic acid ethyl ester in DMSO:water (10:1) was stirred at 120° C. for 2 hours. The reaction mixture was partitioned between ether and 1N HCl, the organic phase was dried with MgSO4 and the solvent removed under reduced pressure.
後処理
- customThe reaction mixture was partitioned between ether and 1N HCl
- dry with materialthe organic phase was dried with MgSO4
- customthe solvent removed under reduced pressure
出典と根拠
- ORDレコード
- ord-d1a6d861cf4a468590e8aa366704d9ac
- 出典データセット
- uspto-grants-2006_08
- 特許番号
- US07084159B2
反応ノート
読み込み中…