Boron tribromide → 5-[4-(5-Fluoro-2-hydroxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentylamino]-quinoline-2-carboxylic acid methylamide

反応式

[B:36]([Br:37])([Br:38])[Br:39].[CH3:1][NH:2][C:3](=[O:4])[c:5]1[n:6][c:7]2[cH:8][cH:9][cH:10][c:11]([NH:15][CH2:16][C:17]([CH2:18][C:19]([CH3:20])([CH3:21])[c:22]3[c:23]([O:29][CH3:30])[cH:24][cH:25][c:26]([F:28])[cH:27]3)([C:31]([F:32])([F:33])[F:34])[OH:35])[c:12]2[cH:13][cH:14]1>>[CH3:1][NH:2][C:3](=[O:4])[c:5]1[n:6][c:7]2[cH:8][cH:9][cH:10][c:11]([NH:15][CH2:16][C:17]([CH2:18][C:19]([CH3:20])([CH3:21])[c:22]3[c:23]([OH:29])[cH:24][cH:25][c:26]([F:28])[cH:27]3)([C:31]([F:32])([F:33])[F:34])[OH:35])[c:12]2[cH:13][cH:14]1

参加物

反応物 2

HCID 25134Boron tribromide

HCID 207862265-[4-(5-Fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentylamino]-quinoline-2-carboxylic acid methylamide

生成物 1

HCID 207862235-[4-(5-Fluoro-2-hydroxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentylamino]-quinoline-2-carboxylic acid methylamide

出典と根拠

ORDレコード: ord-a16cb7a3467d4603a83e725d629b2050
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…