2-Methoxy-6-(2-oxopyrrolidin-1-yl)pyridine-4-carboxylic acid → N-[6-(2-bicyclo[2.2.1]heptanylamino)-3-hydroxy-5-methyl-6-oxo-1-phenylhexan-2-yl]-2-methoxy-6-(2-oxopyrrolidin-1-yl)pyridine-4-carboxamide

反応式

[CH2:1]([CH:2]([NH:3][C:4](=[O:5])[c:6]1[cH:7][c:8](-[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][c:16]([N:17]2[CH2:18][CH2:19][CH2:20][C:21]2=[O:22])[cH:23]1)[CH:24]([OH:25])[CH2:26][CH:27]([C:28](=[O:29])[NH:30][CH2:31][CH2:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH3:37])[c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1.[CH3:44][O:45][c:46]1[n:47][c:48]([N:55]2[C:56](=[O:60])[CH2:57][CH2:58][CH2:59]2)[cH:49][c:50]([C:52](=[O:53])[OH:54])[cH:51]1.[CH:61]12[CH:62]([NH:68][C:69]([CH:70]([CH2:71][CH:72]([CH:73]([CH2:74][c:75]3[cH:76][cH:77][cH:78][cH:79][cH:80]3)[NH2:81])[OH:82])[CH3:83])=[O:84])[CH2:63][CH:64]([CH2:65][CH2:66]1)[CH2:67]2>>[CH3:44][O:45][c:46]1[n:47][c:48]([N:55]2[C:56](=[O:60])[CH2:57][CH2:58][CH2:59]2)[cH:49][c:50]([C:52](=[O:54])[NH:81][CH:73]([CH:72]([CH2:71][CH:70]([C:69]([NH:68][CH:62]2[CH:61]3[CH2:66][CH2:65][CH:64]([CH2:63]2)[CH2:67]3)=[O:84])[CH3:83])[OH:82])[CH2:74][c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)[cH:51]1