5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine → 5-{1-[4-(4-Chloro-3-methyl-phenyl)-6-methyl-pyrimidin-2-yl]-1H-imidazol-4-yl}-pyridin-2-ylamine

反応式

[Cl:1][c:2]1[c:3]([CH3:21])[cH:4][c:5](-[c:8]2[n:9][c:10](-[n:15]3[cH:16][n:17][c:18]([I:20])[cH:19]3)[n:11][c:12]([CH3:14])[cH:13]2)[cH:6][cH:7]1.[NH2:22][c:23]1[n:24][cH:25][c:26]([B:29]2[O:30][C:31]([CH3:32])([CH3:33])[C:34]([CH3:35])([CH3:36])[O:37]2)[cH:27][cH:28]1>>[Cl:1][c:2]1[c:3]([CH3:21])[cH:4][c:5](-[c:8]2[n:9][c:10](-[n:15]3[cH:16][n:17][c:18](-[c:26]4[cH:25][n:24][c:23]([NH2:22])[cH:28][cH:27]4)[cH:19]3)[n:11][c:12]([CH3:14])[cH:13]2)[cH:6][cH:7]1

参加物

反応物 2

HCID 27565555-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine

HCID 574687904-(4-Chloro-3-methyl-phenyl)-2-(4-iodo-imidazol-1-yl)-6-methyl-pyrimidine

生成物 1

HCID 602094515-{1-[4-(4-Chloro-3-methyl-phenyl)-6-methyl-pyrimidin-2-yl]-1H-imidazol-4-yl}-pyridin-2-ylamine

出典と根拠

ORDレコード: ord-ee27411bc1aa45e48e2b86ef2d8de9c5
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…