2-(2-Hydroxymethyl-morpholin-4-yl)-thiazol-4-one → 5-[3-Chloro-1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-(2-hydroxymethyl-morpholin-4-yl)-thiazol-4-one

反応式

[Cl:1][c:2]1[n:3][n:4]([CH2:13][c:14]2[c:15]([C:21]([F:22])([F:23])[F:24])[cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[c:5]2[cH:6][cH:7][c:8]([CH:11]=[O:12])[cH:9][c:10]12.[OH:25][CH2:26][CH:27]1[O:28][CH2:29][CH2:30][N:31]([C:33]2=[N:37][C:36](=[O:38])[CH2:35][S:34]2)[CH2:32]1>>[Cl:1][c:2]1[n:3][n:4]([CH2:13][c:14]2[c:15]([C:21]([F:22])([F:23])[F:24])[cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[c:5]2[cH:6][cH:7][c:8]([CH:11]=[C:35]3[S:34][C:33]([N:31]4[CH2:30][CH2:29][O:28][CH:27]([CH2:26][OH:25])[CH2:32]4)=[N:37][C:36]3=[O:38])[cH:9][c:10]12

参加物

反応物 2

HCID 672406862-(2-Hydroxymethyl-morpholin-4-yl)-thiazol-4-one

HCID 866545953-Chloro-1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehyde

生成物 1

HCID 672405485-[3-Chloro-1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-(2-hydroxymethyl-morpholin-4-yl)-thiazol-4-one

出典と根拠

ORDレコード: ord-9021d91c5cc0489c9f8a45bb06454a0b
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…