化工社化工社 化学情報印刷レポート · 研究参考用
2-Chloro-5-ethylpyrimidine → (3R,4S)-Cyclopropyl-[1-(5-ethyl-pyrimidin-2-yl)-3-fluoro-piperidin-4-yl]-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Chloro-5-ethylpyrimidine | HCID 3572763 | — |
| 反応物 | HCID 68289942 | HCID 68289942 | — |
| 生成物 | (3R,4S)-Cyclopropyl-[1-(5-ethyl-pyrimidin-2-yl)-3-fluoro-piperidin-4-yl]-amine | HCID 68290756 | — |
反応手順
The title compound is prepared from cyclopropyl-[(3R,4S)-3-fluoro-piperidin-4-yl]-carbamic acid tert-butyl ester and 2-chloro-5-ethyl-pyrimidine following a procedure analogous to that described for Intermediate 73.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08822471B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-4f4240851600414389af3338dc926741 |
| 出典メモ | uspto-grants-2014_09 |