化工社化工社 化学情報印刷レポート · 研究参考用
2-Chloro-5-fluoropyrimidine → N-Cyclopropyl-N-[1-(5-fluoro-pyrimidin-2-yl)-piperidin-4-yl]-4-oxazol-5-yl-benzamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Chloro-5-fluoropyrimidine | HCID 583466 | — |
| 反応物 | N-Cyclopropyl-4-oxazol-5-yl-N-piperidin-4-yl-benzamide | HCID 68289931 | — |
| 生成物 | N-Cyclopropyl-N-[1-(5-fluoro-pyrimidin-2-yl)-piperidin-4-yl]-4-oxazol-5-yl-benzamide | HCID 68290806 | — |
反応手順
The title compound is prepared from N-cyclopropyl-4-oxazol-5-yl-N-piperidin-4-yl-benzamide and 2-chloro-5-fluoro-pyrimidine following a procedure analogous to that described in Example 19. LC (method 5): tR=2.14 min; Mass spectrum (ESI+): m/z=408 [M+H]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08822471B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-7326213be58b43bfa68b539879d58d83 |
| 出典メモ | uspto-grants-2014_09 |