[2-(6-Chloro-3-pyridazinyl)-2-azavinyl]dimethylamine → (4-Methoxy-phenyl)-[6-(1-methyl-1h-pyrazol-4-yl)-imidazo[1,2-b]pyridazin-3-yl]-methanone

HRID 69156ノート

反応式

HRID 69156 の反応式
Cl[C:2]1[N:7]=[N:6][C:5](N=CN(C)C)=[CH:4][CH:3]=1.Cl[C:14]1[CH:15]=[CH:16][C:17]2[N:18]([C:20]([C:23]([C:25]3[CH:30]=[CH:29][C:28]([O:31][CH3:32])=[CH:27][CH:26]=3)=[O:24])=[CH:21][N:22]=2)[N:19]=1>>[CH3:32][O:31][C:28]1[CH:29]=[CH:30][C:25]([C:23]([C:20]2[N:18]3[N:19]=[C:14]([C:3]4[CH:2]=[N:7][N:6]([CH3:5])[CH:4]=4)[CH:15]=[CH:16][C:17]3=[N:22][CH:21]=2)=[O:24])=[CH:26][CH:27]=1

参加物

3

反応物 2

HCID 6802247[2-(6-Chloro-3-pyridazinyl)-2-azavinyl]dimethylamineHCID 86635113(6-Chloro-imidazo[1,2-b]pyridazin-3-yl)-(4-methoxy-phenyl)-methanone

生成物 1

HCID 68634302(4-Methoxy-phenyl)-[6-(1-methyl-1h-pyrazol-4-yl)-imidazo[1,2-b]pyridazin-3-yl]-methanone

実験手順

The title compound was prepared in analogy to the synthesis of compound of Example 1, starting with (6-chloro-imidazo[1,2-b]pyridazin-3-yl)-(4-methoxy-phenyl)-methanone (Stage 3.2) (tR 1.1 min (conditions 2), MH+=334)

出典と根拠

ORDレコード
ord-8d47a3d3d7c24b0a9f858cd280b56aa7
出典データセット
uspto-grants-2014_09
特許番号
US08822468B2

反応ノート

読み込み中…