Hydrogen chloride-ethyl acetate → 4-Methoxybutyric acid hydrazide hydrochloride salt

N′-(4-Methoxybutyryl)hydrazine carboxylic acd tert-butyl ester (9.30 g) was dissolved in ethyl acetate (50 ml), followed by addition of 4 mol/liter hydrochloric acid/ethyl acetate solution (150 ml), and stirred at ambient temperature for 2 hours. After the reaction solution was concentrated under reduced pressure, the resulting residue was washed with n-hexane, to afford 4-methoxybutyric acid hydrazide hydrochloride salt as pale yellow solid (5.99 g, 89%). The physico-chemical values are as follows.

1. concentrationAfter the reaction solution was concentrated under reduced pressure
2. washthe resulting residue was washed with n-hexane

ORDレコード

ord-2f1fc4e63bcd49baab4faaaf5cb38cf8

出典データセット

uspto-grants-2006_08

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US07084164B2