HCID 21105432、化合物 → 6-butoxy-2-[4-(1,4-dioxa-7-azaspiro[4.4]non-7-yl)phenyl]-3,4-dihydro-2H-isoquinolin-1-one

HRID 69420

反応式

HRID 69420 の反応式
[O:1]1[C:5]2([CH2:9][CH2:8][N:7]([C:10]3[CH:15]=[CH:14][C:13]([NH2:16])=[CH:12][CH:11]=3)[CH2:6]2)[O:4][CH2:3][CH2:2]1.[CH2:17]([O:21][C:22]1[CH:30]=[CH:29][C:25]([C:26](Cl)=[O:27])=[C:24]([CH2:31][CH2:32]Cl)[CH:23]=1)[CH2:18][CH2:19][CH3:20]>>[CH2:17]([O:21][C:22]1[CH:23]=[C:24]2[C:25](=[CH:29][CH:30]=1)[C:26](=[O:27])[N:16]([C:13]1[CH:14]=[CH:15][C:10]([N:7]3[CH2:8][CH2:9][C:5]4([O:4][CH2:3][CH2:2][O:1]4)[CH2:6]3)=[CH:11][CH:12]=1)[CH2:32][CH2:31]2)[CH2:18][CH2:19][CH3:20]

参加物

3

反応物 2

HCID 21105432HCID 21105432、化合物HCID 534401334-Butoxy-2-(2-chloroethyl)benzoyl chloride

生成物 1

HCID 689920606-butoxy-2-[4-(1,4-dioxa-7-azaspiro[4.4]non-7-yl)phenyl]-3,4-dihydro-2H-isoquinolin-1-one

実験手順

4-(1,4-Dioxa-7-azaspiro[4.4]non-7-yl)phenylamine was reacted with 4-butoxy-2-(2-chloroethyl)benzoyl chloride by method A. The product with the molecular weight of 438.57 (C26H34N2O4) was obtained in this way; MS (ESI): 439 (M+H+).

後処理

  1. customThe product with the molecular weight of 438.57 (C26H34N2O4) was obtained in this way

出典と根拠

ORDレコード
ord-5d942b5b38ea4ffbb474b5c037698a52
出典データセット
uspto-grants-2014_09
特許番号
US08822495B2

関連ノート

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