化工社化工社 化学情報印刷レポート · 研究参考用
Butanal → 1,1-Di-(7-azaindol-3-yl)-butane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Butanal | HCID 261 | — |
| 反応物 | 1H-Pyrrolo(2,3-b)pyridine | HCID 9222 | — |
| 生成物 | 1,1-Di-(7-azaindol-3-yl)-butane | HCID 22019283 | 15% |
反応手順
ST 1436 was prepared as described in example 2/2 from 7-azaindole and butyraldehyde. The reaction, however, was heated under reflux for 48 hours. The end product was isolated and purified chromatographically on a silica column eluting with a CH2Cl2:CH3COCH3 gradient ranging from 9:1 to 4:6. Yield 15%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07084166B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-7e699b14c36a4cb1ab9bfad78d80f704 |
| 出典メモ | uspto-grants-2006_08 |