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N-Formylmorpholine → 6-Benzyloxy-2-((R)-4-[1,3']bipyrrolidinyl-1'-yl-3-methoxy-phenyl)-2H-isoquinolin-1-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-Formylmorpholine | HCID 20417 | — |
| 反応物 | 4-benzyloxy-N-((R)-4-[1,3']bipyrrolidinyl-1'-yl-3-methoxy-phenyl)-2-methyl-benzamide | HCID 68988853 | — |
| 生成物 | 6-Benzyloxy-2-((R)-4-[1,3']bipyrrolidinyl-1'-yl-3-methoxy-phenyl)-2H-isoquinolin-1-one | HCID 68990095 | — |
反応手順
According to Method Q, 4-benzyloxy-N—((R)-4-[1,3′]bipyrrolidinyl-1′-yl-3-methoxy-phenyl)-2-methyl-benzamide was reacted with N-formylmorpholine. In this way the product was obtained with molecular weight 495.63 (C31H33N3O3); MS (ESI): 496 (M+H+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08822495B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-c03e5af6b18b47b098c8f2fbfa3a8f17 |
| 出典メモ | uspto-grants-2014_09 |