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4-Bromo-3-fluoroaniline → 2-(4-Bromo-3-fluorophenyl)-6-[(R)-1-(tetrahydrofuran-2-yl)methoxy]-2H-isoquinolin-1-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Bromo-3-fluoroaniline | HCID 821848 | — |
| 反応物 | 6-[(R)-1-(Tetrahydrofuran-2-yl)methoxy]isochromen-1-one | HCID 66878936 | — |
| 生成物 | 2-(4-Bromo-3-fluorophenyl)-6-[(R)-1-(tetrahydrofuran-2-yl)methoxy]-2H-isoquinolin-1-one | HCID 68991216 | — |
反応手順
6-[(R)-1-(Tetrahydrofuran-2-yl)methoxy]-isochromen-1-one and 4-bromo-3-fluorophenylamine were reacted according to Method AJ. In this way the product was obtained with molecular weight 418.27 (C20H17BrFNO3); MS (ESI): 418 and 420 (M+H+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08822495B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-3e2231314d8945f984affa0192254ed6 |
| 出典メモ | uspto-grants-2014_09 |