1,4-Difluoro-2-isocyanatobenzene → N-(1-benzylpyrrolidin-3-yl)-2-[(2,5-difluorophenyl)carbamoylamino]-3,3-dimethylbutanamide

反応式

[F:1][c:2]1[c:3]([N:9]=[C:10]=[O:11])[cH:4][c:5]([F:8])[cH:6][cH:7]1.[NH2:12][CH:13]([C:14](=[O:15])[NH:16][CH:17]1[CH2:18][N:19]([CH2:22][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[CH2:20][CH2:21]1)[C:29]([CH3:30])([CH3:31])[CH3:32]>>[F:1][c:2]1[c:3]([NH:9][C:10](=[O:11])[NH:12][CH:13]([C:14](=[O:15])[NH:16][CH:17]2[CH2:18][N:19]([CH2:22][c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[CH2:20][CH2:21]2)[C:29]([CH3:30])([CH3:31])[CH3:32])[cH:4][c:5]([F:8])[cH:6][cH:7]1

参加物

反応物 2

HCID 27332661,4-Difluoro-2-isocyanatobenzene

HCID 219386822-amino-N-(1-benzylpyrrolidin-3-yl)-3,3-dimethylbutanamide

生成物 1

HCID 21938689N-(1-benzylpyrrolidin-3-yl)-2-[(2,5-difluorophenyl)carbamoylamino]-3,3-dimethylbutanamide

出典と根拠

ORDレコード: ord-351526ea464d48968726a79e3bfebfb6
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…