2-(Thiazol-4-yl)thiophen-3-amine → 2-(2-oxo-3,4-dihydro-1,6-naphthyridin-1(2H)-yl)-N-(2-(thiazol-4-yl)thiophen-3-yl)acetamide

反応式

[O:1]=[C:2]1[N:3]([CH2:12][C:13](=[O:14])[OH:15])[c:4]2[cH:5][cH:6][n:7][cH:8][c:9]2[CH2:10][CH2:11]1.[s:16]1[cH:17][n:18][c:19](-[c:21]2[s:22][cH:23][cH:24][c:25]2[NH2:26])[cH:20]1>>[O:1]=[C:2]1[N:3]([CH2:12][C:13](=[O:15])[NH:26][c:25]2[c:21](-[c:19]3[n:18][cH:17][s:16][cH:20]3)[s:22][cH:23][cH:24]2)[c:4]2[cH:5][cH:6][n:7][cH:8][c:9]2[CH2:10][CH2:11]1

参加物

反応物 2

HCID 687553622-(Thiazol-4-yl)thiophen-3-amine

HCID 687868432-(2-oxo-3,4-dihydro-1,6-naphthyridin-1(2H)-yl)acetic acid

生成物 1

HCID 468689962-(2-oxo-3,4-dihydro-1,6-naphthyridin-1(2H)-yl)-N-(2-(thiazol-4-yl)thiophen-3-yl)acetamide

出典と根拠

ORDレコード: ord-eae8e347b54449569d811bd87e95fc42
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…