Dichloromethane → 8'-fluoro-5'-hydroxy-1'H-spiro[cyclohexane-1,4'-quinazolin]-2'(3'H)-one

反応式

[B:20]([Br:21])([Br:22])[Br:23].[C:27]([O:28][CH3:29])([CH3:30])([CH3:31])[CH3:32].[Cl:24][CH2:25][Cl:26].[F:1][c:2]1[cH:3][cH:4][c:5]([O:18][CH3:19])[c:6]2[c:7]1[NH:8][C:9](=[O:17])[NH:10][C:11]21[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([OH:18])[c:6]2[c:7]1[NH:8][C:9](=[O:17])[NH:10][C:11]21[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]1