6-Piperazino-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine → 6-[4-[[3-(Difluoromethoxy)phenyl]methyl]piperazin-1-yl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine

反応式

[F:20][CH:21]([O:22][c:23]1[cH:24][c:25]([CH:26]=[O:27])[cH:28][cH:29][cH:30]1)[F:31].[N:1]1([c:7]2[cH:8][cH:9][c:10]3[n:11]([n:12]2)[c:13]([C:16]([F:17])([F:18])[F:19])[n:14][n:15]3)[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1>>[N:1]1([c:7]2[cH:8][cH:9][c:10]3[n:11]([n:12]2)[c:13]([C:16]([F:17])([F:18])[F:19])[n:14][n:15]3)[CH2:2][CH2:3][N:4]([CH2:26][c:25]2[cH:24][c:23]([O:22][CH:21]([F:20])[F:31])[cH:30][cH:29][cH:28]2)[CH2:5][CH2:6]1

参加物

反応物 2

HCID 14768626-Piperazino-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine

HCID 27369853-(Difluoromethoxy)benzaldehyde

生成物 1

HCID 673409076-[4-[[3-(Difluoromethoxy)phenyl]methyl]piperazin-1-yl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine

出典と根拠

ORDレコード: ord-6a398f6ada4f4f4b820c34c9b3ec59aa
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…