2-(6-bromo-1H-benzimidazol-2-yl)pyrrolidine-1-carboxylic acid tert-butyl ester → 6-Bromo-2-pyrrolidin-2-yl-1H-benzoimidazole

反応式

[C:29]([O:30][C:31](=[O:32])[N:36]1[CH:37]([c:41]2[n:42][c:43]3[c:44]([nH:45]2)[cH:46][c:47]([Br:50])[cH:48][cH:49]3)[CH2:38][CH2:39][CH2:40]1)([CH3:33])([CH3:34])[CH3:35].[CH3:1][O:2][C:3](=[O:4])[NH:5][CH:6]([C:7]([N:8]1[CH2:9][CH2:10][CH2:11][CH:12]1[c:13]1[nH:14][c:15](-[c:16]2[cH:17][cH:18][c:19]([Br:20])[cH:21][cH:22]2)[cH:23][n:24]1)=[O:25])[CH:26]([CH3:27])[CH3:28]>>[NH:36]1[CH:37]([c:41]2[n:42][c:43]3[c:44]([nH:45]2)[cH:46][c:47]([Br:50])[cH:48][cH:49]3)[CH2:38][CH2:39][CH2:40]1

参加物

反応物 2

HCID 581852752-(6-bromo-1H-benzimidazol-2-yl)pyrrolidine-1-carboxylic acid tert-butyl ester

HCID 66620141Methyl (1-(2-(4-(4-bromophenyl)-1H-imidazol-2-YL)pyrrolidin-1-YL)-3-methyl-1-oxobutan-2-YL)carbamate

生成物 1

HCID 607848906-Bromo-2-pyrrolidin-2-yl-1H-benzoimidazole

出典と根拠

ORDレコード: ord-0dd571ef6458413f868f5b261c538dda
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…