Acetic Acid → 5-{4-(6-Bromo-3-methylimidazo[5,4-b]pyridin-2-ylmethoxy)benzyl}thiazolidine-2,4-dione

反応式

[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([CH3:46])[c:9]([CH2:11][O:12][c:13]1[cH:14][cH:15][c:16]([CH2:17][CH:18]3[C:19](=[O:43])[N:20]([C:24]([c:25]4[cH:26][cH:27][cH:28][cH:29][cH:30]4)([c:31]4[cH:32][cH:33][cH:34][cH:35][cH:36]4)[c:37]4[cH:38][cH:39][cH:40][cH:41][cH:42]4)[C:21](=[O:23])[S:22]3)[cH:44][cH:45]1)[n:10]2.[CH3:47][C:48](=[O:49])[OH:50].[OH2:51]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([CH3:46])[c:9]([CH2:11][O:12][c:13]1[cH:14][cH:15][c:16]([CH2:17][CH:18]3[C:19](=[O:43])[NH:20][C:21](=[O:23])[S:22]3)[cH:44][cH:45]1)[n:10]2

参加物

反応物 3

HCID 176Acetic Acid

HCID 962Water

HCID 107471775-{4-(6-Bromo-3-methylimidazo[5,4-b]pyridin-2-ylmethoxy)benzyl}-3-triphenylmethylthiazolidine-2,4-dione

生成物 1

HCID 117976605-{4-(6-Bromo-3-methylimidazo[5,4-b]pyridin-2-ylmethoxy)benzyl}thiazolidine-2,4-dione

出典と根拠

ORDレコード: ord-f1d7fc25919e4d838e8195d7e5c271de
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…