Methanesulfonyl chloride → N-[3-(2-chloro-pyrimidin-4-yl)-benzyl]-N-(2-pyridin-4-yl-ethyl)-methanesulfonamide

反応式

[CH3:24][S:25]([Cl:26])(=[O:27])=[O:28].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][c:10]([CH2:11][NH:12][CH2:13][CH2:14][c:15]3[cH:16][cH:17][n:18][cH:19][cH:20]3)[cH:21][cH:22][cH:23]2)[n:7]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][c:10]([CH2:11][N:12]([CH2:13][CH2:14][c:15]3[cH:16][cH:17][n:18][cH:19][cH:20]3)[S:25]([CH3:24])(=[O:27])=[O:28])[cH:21][cH:22][cH:23]2)[n:7]1

参加物

反応物 2

HCID 31297Methanesulfonyl chloride

HCID 86603257N-(3-(2-chloropyrimidin-4-yl)benzyl)-2-(pyridine-4-yl)ethanamine

生成物 1

HCID 86603258N-[3-(2-chloro-pyrimidin-4-yl)-benzyl]-N-(2-pyridin-4-yl-ethyl)-methanesulfonamide

出典と根拠

ORDレコード: ord-4300f5e9b00b46ce85863cab4e38fbf3
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…