Water → Tert-butyl (5-((trimethylsilyl)ethynyl)thiazol-2-yl)carbamate

HRID 702861ノート

反応式

HRID 702861 の反応式
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[s:9][c:10]([Br:13])[cH:11][n:12]1)=[O:14].[CH3:15][Si:16]([CH3:17])([CH3:18])[C:19]#[CH:20].[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28].[Cu:29][I:30].[OH2:21]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[s:9][c:10]([C:20]#[C:19][Si:16]([CH3:15])([CH3:17])[CH3:18])[cH:11][n:12]1)=[O:14]

参加物

6

反応物 5

HCID 962WaterHCID 8471TriethylamineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66111TrimethylsilylacetyleneHCID 21300388tert-butyl N-(5-bromo-1,3-thiazol-2-yl)carbamate

生成物 1

HCID 45117882Tert-butyl (5-((trimethylsilyl)ethynyl)thiazol-2-yl)carbamate

出典と根拠

ORDレコード
ord-f00ffefdf3a34433997f933de057b6de
出典データセット
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

反応ノート

読み込み中…