Hydrochloric Acid → 5,7-dihydro-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]-5,5,7,7-tetramethylindeno[5,6-d]imidazol-6(1H)-one dihydrochloride
反応式
[CH3:1][O:2][C:3]1[C:8]([CH3:9])=[CH:7][N:6]=[C:5]([CH2:10][S:11][C:12]2[NH:16][C:15]3[CH:17]=[C:18]4[C:22](=[CH:23][C:14]=3[N:13]=2)[C:21]([CH3:25])([CH3:24])[C:20](=[O:26])[C:19]4([CH3:28])[CH3:27])[C:4]=1[CH3:29].[ClH:30]>CO>[ClH:30].[ClH:30].[CH3:1][O:2][C:3]1[C:8]([CH3:9])=[CH:7][N:6]=[C:5]([CH2:10][S:11][C:12]2[NH:13][C:14]3[CH:23]=[C:22]4[C:18](=[CH:17][C:15]=3[N:16]=2)[C:19]([CH3:27])([CH3:28])[C:20](=[O:26])[C:21]4([CH3:25])[CH3:24])[C:4]=1[CH3:29]参加物
4
反応物 2
生成物 1
試薬・触媒・溶媒 1
実験手順
2.6 g of 5,7-dihydro-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]-5,5,7,7-tetram ethylindeno[5,6-d]imidazol-6(lH)-one were dissolved in 50 ml of hot methanol and the solution was boiled under reflux for 10 minutes with 50 ml of a 4N solution of hydrogen chloride in methanol. After concentration in vacuo the residue was crystallized from ether and there was obtained 5,7-dihydro-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]-5,5,7 ,7-tetramethylindeno[5,6-d]imidazol-6(lH)-one dihydrochloride of melting point 165-170° .