化工社化工社 化学情報印刷レポート · 研究参考用
Acetic Acid → 3-((2-amino-4-chlorophenyl)thio)-N,N-dimethylpropanamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | 2-Amino-4-chlorobenzenethiol | HCID 12000 | — |
| 反応物 | N,N-Dimethylacrylamide | HCID 17587 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 3-((2-amino-4-chlorophenyl)thio)-N,N-dimethylpropanamide | HCID 60961870 | 83% |
反応手順
The solution of 2-amino-4-chlorobenzenethiol (824 mg, 5.126 mmol), N,N-dimethylacrylamide (512 mg, 5.162 mmol), and HOAc (1 ml) in CH2Cl2 (10 ml) was stirred at room temperature for 4 days. The solvent was removed and the residue was loaded on silica column and purified to yield a white solid (1.08 g, 83%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08822530B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-d56a93cafd944ebe8d2c4ac166229472 |
| 出典メモ | uspto-grants-2014_09 |