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Triphenylphosphine → HCID 178453006、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triphenylphosphine | HCID 11776 | — |
| 反応物 | 2-Amino-4-chlorobenzenethiol | HCID 12000 | — |
| 反応物 | Di-tert-butyl diazene-1,2-dicarboxylate | HCID 6034084 | — |
| 反応物 | HCID 178453005 | HCID 178453005 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | HCID 178453006 | HCID 178453006 | — |
反応手順
A solution of tert-butyl (5-(hydroxymethyl)-4H-1,2,4-triazol-3-yl)carbamate (190 mg, 0.888 mmol), 2-amino-4-chlorobenzenethiol (213 mg, 1.332 mmol), PPh3 (466 mg, 1.776 mmol) and di-tert-butylazodicarboxylate (409 mg, 1.776 mmol) in CH2Cl2 (10 ml) was stirred at room temperature for 2 days. The solvent was then removed and the crude residues was loaded on silica gel column to get the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08822530B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-26e7f3bb0d004fe48de4f7eeeebe439b |
| 出典メモ | uspto-grants-2014_09 |