Sulfuric Acid → HCID 85552580、化合物
反応式
[C:1]([C:5]([C:7]1[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9][CH:8]=1)=O)([CH3:4])([CH3:3])[CH3:2].[CH3:14][NH:15][NH2:16].S(=O)(=O)(O)O>C(O)C>[CH3:14][NH:15][N:16]=[C:5]([C:1]([CH3:4])([CH3:3])[CH3:2])[C:7]1[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9][CH:8]=1参加物
5
実験手順
29.5 g ofg 4-chlorophenyl tert.-butyl ketone (0.15 mol) in 750 ml ethanol was heated under reflux with an excess (118 ml) of methl hydrazine and 3 ml of concentrated sulphuric acid for 4.5 hours. It was concentrated almost to dryness and the added to water. After extraction with methylene chloride and then drying and concentrating the extract in vacuo, there was obtained an oil which eventually crystallised. The resulting crude product used immediately.
後処理
- concentrationIt was concentrated almost to dryness
- additionthe added to water
- extractionAfter extraction with methylene chloride
- customdrying
- concentrationconcentrating the
- extractionextract in vacuo
- customthere was obtained an oil which
- customeventually crystallised
出典と根拠
- ORDレコード
- ord-beebd25ad6274fa18fe8c1bdf83185db
- 出典データセット
- uspto-grants-1991_01
- 特許番号
- US04983755
反応ノート
読み込み中…