1,1,1-Trimethoxy-2-methylpropane → N-(1-Methoxy-2-methylpropylidene)-3-phenyl-1,2,4-thiadiazole-5-sulfonamide

HRID 704029

反応式

HRID 704029 の反応式
[C:1]1([C:7]2[N:11]=[C:10]([S:12]([NH2:15])(=[O:14])=[O:13])[S:9][N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:16](OC)(OC)([O:20][CH3:21])[CH:17]([CH3:19])[CH3:18]>CCCCCC>[CH3:21][O:20][C:16](=[N:15][S:12]([C:10]1[S:9][N:8]=[C:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[N:11]=1)(=[O:14])=[O:13])[CH:17]([CH3:19])[CH3:18]

参加物

4

反応物 2

HCID 404951,1,1-Trimethoxy-2-methylpropaneHCID 141831323-Phenyl-1,2,4-thiadiazole-5-sulfonamide

生成物 1

HCID 53780129N-(1-Methoxy-2-methylpropylidene)-3-phenyl-1,2,4-thiadiazole-5-sulfonamide

試薬・触媒・溶媒 1

HCID 8058Hexane溶媒

実験手順

A mixture of 3 g of 3-phenyl-1,2,4-thiadiazole-5-sulfonamide and and 11 ml of trimethyl orthoisobutyrate was warmed to about 90° using an oil bath. After 2.5 hours, the solution was allowed to cool to room temperature, whereupon a precipitate formed. Hexane (25 ml) was added to complete the precipitation. The solid was collected, washed with hexane and vacuum dried (P2O5) to give 3.34 g of solid, m.p. 123°-124°.

後処理

  1. temperaturewas warmed to about 90°
  2. customformed
  3. customthe precipitation
  4. customThe solid was collected
  5. washwashed with hexane and vacuum
  6. dry with materialdried (P2O5)

出典と根拠

ORDレコード
ord-4f1dd26df44044e5bdd3078f719b304e
出典データセット
uspto-grants-1991_01
特許番号
US04985450

関連ノート

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